国产青榴社区91精品,久久成人精品免费播放,久久精品人人做人人试看

Home> Market activity > Achievements > article shows > article details

Virome comparisons in wild-diseased and healthy captive giant pandas

2017-12-15


Abstract 

Background: 

The giant panda (Ailuropoda melanoleuca) is a vulnerable mammal herbivore living wild in central China. Viral infections have become a potential threat to the health of these endangered animals, but limited information related to these infections is available. 

Methods: 

Using a viral metagenomic approach, we surveyed viruses in the feces, nasopharyngeal secretions, blood, and different tissues from a wild giant panda that died from an unknown disease, a healthy wild giant panda, and 46 healthy captive animals. 

Results: 

The previously uncharacterized complete or near complete genomes of four viruses from three genera in Papillomaviridae family, six viruses in a proposed new Picornaviridae genus (Aimelvirus), two unclassified viruses related to posaviruses in Picornavirales order, 19 anelloviruses in four different clades of Anelloviridae family, four putative circoviruses, and 15 viruses belonging to the recently described Genomoviridae family were sequenced. Reflecting the diet of giant pandas, numerous insect virus sequences related to the families Iflaviridae, Dicistroviridae, Iridoviridae, Baculoviridae, Polydnaviridae, and subfamily Densovirinae and plant viruses sequences related to the families Tombusviridae, Partitiviridae, Secoviridae, Geminiviridae, Luteoviridae, Virgaviridae, and Rhabdoviridae; genus Umbravirus, Alphaflexiviridae, and Phycodnaviridae were also detected in fecal samples. A small number of insect virus sequences were also detected in the nasopharyngeal secretions of healthy giant pandas and lung tissues from the dead wild giant panda. Although the viral families present in the sick giant panda were also detected in the healthy ones, a higher proportion of papillomaviruses, picornaviruses, and anelloviruses reads were detected in the diseased panda. 

Conclusion: 

This viral survey increases our understanding of eukaryotic viruses in giant pandas and provides a baseline for comparison to viruses detected in future infectious disease outbreaks. The similar viral families detected in sick and healthy giant pandas indicate that these viruses result in commensal infections in most immuno-competent animals. 

Keywords:

 Giant panda, Viral metagenomics, Virome, Papillomavirus, Picornavirus, Anellovirus, Gemycircularvirus, Putative circovirus

Link text:

https://doi.org/10.1186/s40168-017-0308-0


主站蜘蛛池模板: 林周县| 蒙山县| 唐河县| 南郑县| 晴隆县| 龙川县| 繁昌县| 防城港市| 崇礼县| 湘乡市| 蕲春县| 四川省| 句容市| 准格尔旗| 曲麻莱县| 谢通门县| 嵊泗县| 临湘市| 盖州市| 盖州市| 德庆县| 北安市| 大冶市| 岑巩县| 德惠市| 泉州市| 六枝特区| 锡林郭勒盟| 扎鲁特旗| 汤阴县| 稻城县| 齐河县| 石楼县| 绍兴县| 晋中市| 宜宾县| 广州市| 依兰县| 蛟河市| 观塘区| 中阳县|